Gastrointestinal stromal tumor in vagina: A case report.

Ha, Seung Yeon; Lee, Ki Beom; Lee, Soon Pyo

doi:2011.54.10.639

Case Report

Korean Journal of Obstetrics & Gynecology 2011;54(10):639-642.
DOI: https://doi.org/10.5468/KJOG.2011.54.10.639 Published online October 1, 2011.

Gastrointestinal stromal tumor in vagina: A case report.

Seung Yeon Ha, Ki Beom Lee, Soon Pyo Lee

¹Department of Pathology, Gachon University Gil Hospital, Incheon, Korea.
²Department of Obstetrics and Gynecology, Gachon University Gil Hospital, Incheon, Korea. syha@gilhospital.com

Abstract

Gastrointestinal stromal tumor (GIST) is a mesenchymal tumor that usually arises within the gastrointestinal tract. However extragastrointestinal stromal tumor (EGIST) is a rare tumor (5%), especially few cases of EGIST arising in vagina have currently been reported in the literature. We have experienced a case of vaginal GIST. A 49-year-old female presented with vaginal mass for three weeks. The mass was located posterolateral vagina near to introitus and 3.0 x 2.5 cm in size. Histological examination showed hypercelluar spindle cell proliferation and more than 10 mitoses per 50 high power fields. They were positive for c-kit (CD 117) and CD34. Surgery is the most effective treatment and long term follow up is warranted.

Key Words: Gastrointestinal stromal tumor, Vagina