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Obstet Gynecol Sci > Volume 54(3); 2011 > Article
Korean Journal of Obstetrics & Gynecology 2011;54(3):147-150.
DOI: https://doi.org/10.5468/KJOG.2011.54.3.147    Published online March 1, 2011.
A case report on successful pregnancy and delivery in a medulloblastoma patient.
Se Hyoun Kwak, In Yang Park, Ji Sun We, Mi Rang Choi, Jong Chul Shin
Department of Obstetrics and Gynecology, The Catholic University of Korea School of Medicine, Seoul, Korea. jcshin@catholic.ac.kr
Abstract
Medulloblastomas are rare neoplasms in adults. Medulloblastomas are treated by surgical removal of the tumor followed by radiotherapy. Because craniospinal irradiation can damage the hypothalamic-pituitary axis, uterus, and ovaries, and consequently result in infertility, the probability of pregnancy is quite low. We managed a patient who had undergone resection of a posterior fossa medulloblastoma and received craniospinal irradiation, who conceived spontaneously during follow-up. She was diagnosed with a recurrent medulloblastoma with metastasis to the spine accompanied by headaches and back pain at 26 weeks gestation. Conservative treatment measures were utilized in an effort to prolong the pregnancy. She was delivered by cesarean section due to recurrent seizure activity at 29 weeks plus 3 days gestation. The neonate made favorable progress and was discharged in good condition.
Key Words: Medulloblastoma, Recurrence, Metastasis, Pregnancy


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