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Obstet Gynecol Sci > Volume 54(6); 2011 > Article
Korean Journal of Obstetrics & Gynecology 2011;54(6):330-333.
DOI: https://doi.org/10.5468/KJOG.2011.54.6.330    Published online June 1, 2011.
Angiomyofibroblastoma of the uterine cervix in a breast cancer patient: A case report.
Min Ji Kim, Ji Ni Kuk, Ji Hyun Sung, Chang Lim Hyun, Soon Sup Shim, Chul Min Park, Sung Yob Kim
1Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
2Department of Pathology, Jeju National University School of Medicine, Jeju, Korea.
3Department of Obstetrics and Gynecology, Jeju National University School of Medicine, Jeju, Korea. kimsy@cheju.ac.kr
Angiomyofibroblastoma (AMFB) is a rare mesenchymal tumor mostly involving the female lower genital tract. Although a large number of cases of vulva and vagina has been reported, a report on a case of the uterine cervix is uncommon. Despite unknown pathogenesis of AMFB, positive immunoreactivity for hormonal receptor of AMFB allows to make an assumption that the hormonal stimuli may have a role on the development of AMFB. Therefore, it is potential that estrogenic effect of tamoxifen gives stimuli on hormonally responsible mesenchymal cells, resulting in AMFB. We report a case of AMFB of the uterine cervix in a breast cancer patient with prolonged tamoxifen treatment with brief literature review.
Key Words: Angiomyofibroblastoma, Cervix uteri, Breast neoplasm, Tamoxifen

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