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Obstet Gynecol Sci > Volume 54(7); 2011 > Article
Korean Journal of Obstetrics & Gynecology 2011;54(7):349-354.
DOI: https://doi.org/10.5468/KJOG.2011.54.7.349    Published online July 1, 2011.
The Correlation of cervical intraepithelial neoplasia 3 detected by cervical punch biopsies with the pathologic results of conization and hysterectomy.
Ki Won Kim, Kyoung Mi Kim, Jung Woo Park, Hyun Jae Jung, Jee Young Han, Joon Mee Kim, Jee Hyun Park, Sung Ook Hwang, Woo Young Lee, Eunseop Song
1Department of Obstetrics and Gynecology, Inha University College of Medicine, Incheon, Korea. songsong2000@hotmail.com
2Department of Pathology, Inha University College of Medicine, Incheon, Korea.
To know the correlation of punch-biopsy proven cervical intraepithelial neoplasia (CIN) 3 with the results of cone and hysterectomy. METHODS: We reviewed the medical records from 1999 to 2008, retrospectively, at a single institution. We checked age, cone and hysterectomy biopsy results, preoperative cervical smear results as well as human papillomavirus results. RESULTS: There were 104 patients whose punch biopsy results were CIN 3. 59 (56.7%) patients underwent cone and 45 did hysterectomy after punch biopsies. Cone found 6.8% of cervical cancer. Among patients undergoing hysterectomy without cone, 8.9% had cervical cancers. There were a lot of inflammations, atypical squamous cells of unknown significance, low-grade squamous intraepithelial lesion done as a Pap results just before cone. The positive rate of HPV was 80.0%. There were 5.1% of under-estimated and 6.8% of over-estimated results according to the cone results, and 6.7% of under-estimated and 8.9% of over-estimated according to the hysterectomy results. CONCLUSION: Through conization, 93.2% of the patients whose punch biopsy results were CIN 3 had CIN and did not need hysterectomy, and 6.8% had cervical cancers and might need further treatment. Through hysterectomy, 91.2% had CIN and might undergo overtreatment.
Key Words: Cervical intraepithelial neoplasia, Uterine cervical cancer, Biopsy, Conization, Hysterectomy

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