Primary signet ring cell carcinoma of the uterine cervix: A case report.

Yoon, Aera; Kim, Seo Hee; Kim, Ha Jeong; Bae, Duk Soo; Lee, Jeong Won

doi:2011.54.9.570

Case Report

Korean Journal of Obstetrics & Gynecology 2011;54(9):570-573.
DOI: https://doi.org/10.5468/KJOG.2011.54.9.570 Published online September 1, 2011.

Primary signet ring cell carcinoma of the uterine cervix: A case report.

Aera Yoon, Seo Hee Kim, Ha Jeong Kim, Duk Soo Bae, Jeong Won Lee

Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. garden.lee@samsung.com

Abstract

Primary signet ring cell carcinoma of the cervix is extremely rare. A 47-year-old woman visited for postcoital vaginal bleeding during the last six months. Gynecologic examination revealed mild cervical erosion and touch bleeding. Colposcopic punch biopsy revealed a signet ring cell type of mucinous adenocarcinoma. The patient underwent radical hysterectomy with bilateral salpingo-oophorectomy, pelvic lymph node dissection, and para-aortic lymph node dissection. Microscopically, the tumor mainly consisted of two different types of cells; mixed signet ring cell carcinoma (70%) and mucinous carcinoma of intestinal type (30%). The patient died in 6 months after operation. The prognosis of primary signet ring cell adenocarcinoma of the uterine cervix is still unclear because of the extremely rare incidence of cases. In this case, we could suggest that this type of carcinoma has an aggressive behavior.

Key Words: Signet ring cell carcinoma, Uterine cervical neoplasm, Adenocarcinoma