Two cases of rare heterotopic pregnancy following in vitro fertilization and embryo transfer.

Cho, Hie Jin; Park, Soo jin; Ok, Ji Hoon; Choi, Jong Ryeol; Kim, Tae Gyun; Lee, Kyu Sup

doi:2011.54.12.802

Obstet Gynecol Sci > Volume 54(12); 2011 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 2011;54(12):802-806.
DOI: https://doi.org/10.5468/KJOG.2011.54.12.802 Published online December 1, 2011.

Two cases of rare heterotopic pregnancy following in vitro fertilization and embryo transfer.

Hie Jin Cho, Soo jin Park, Ji Hoon Ok, Jong Ryeol Choi, Tae Gyun Kim, Kyu Sup Lee

¹Department of Obstetrics and Gynecology, Wallace Memorial Baptist Hospital, Busan, Korea. ktggyn@gmail.com
²Mirae Obstetrics and Gynecology Hospital, Busan, Korea.
³Department of Obstetrics and Gynecology, Pusan National University School of Medicine, Busan, Korea. kuslee@pusan.ac.kr

Abstract

Heterotopic pregnancy has been traditionally considered a rare event; however, with the use of assisted reproductive technology, the incidence of heterotopic pregnancies is increasing. Early diagnosis of heterotopic pregnancy is often difficult because clinical symptoms and signs are not specific. We experienced two rare cases of heterotopic pregnancy following in vitro fertilization and embryo transfer. First case was the triplet pregnancy, which was combined one intrauterine pregnancy and two extrauterine pregnancy in bilateral tube. Second case was the unruptured heterotopic pregnancy by midtrimester, which had not any symptom and was diagnosed by ultrasound. We report two cases of rare heterotopic pregnancy following in vitro fertilization with brief review of literature.

Key Words: Pregnancy, combined, In vitro fertilization, Embryo transfer, Pregnancy, tubal, bilateral, Midtrimester