Metastatic gestational choriocarcinoma as initial presentation of intracerebral hemorrhage: A case report.

Lee, Young Jin; Kim, Ari; Cho, Hae Joong; Park, Seong Nam; Hong, Sung Nam; Kim, Heung Yeol

doi:2012.55.5.348

Case Report

Korean Journal of Obstetrics & Gynecology 2012;55(5):348-352.
DOI: https://doi.org/10.5468/KJOG.2012.55.5.348 Published online May 16, 2012.

Metastatic gestational choriocarcinoma as initial presentation of intracerebral hemorrhage: A case report.

Young Jin Lee, Ari Kim, Hae Joong Cho, Seong Nam Park, Sung Nam Hong, Heung Yeol Kim

¹Department of Obstetrics and Gynecology, Kosin University College of Medicine, Busan, Korea. ttochil@hanmail.net
²Department of Obstetrics and Gynecology, Wonkwang University College of Medicine, Iksan, Korea.
³Department of Obstetrics and Gynecology, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.

Abstract

Choriocarcinoma is the most malignant tumor of gestational trophoblastic neoplasia, which grows rapidly and metastasizes to the lung, liver, and, less frequently, brain. This tumor is known for its association with molar pregnancy, rapid hematogenous spread to multiple organs, high human chorionic gonadotropin levels, and good response to chemotherapy. Metastases to the brain are responsible for most of the deaths from choriocarcinoma. Its prognosis is generally good when treated. We report a rare case of metastatic gestational choriocarcinoma as an initial presentation of intracerebral hemorrhage.

Key Words: Brain, Gestational choriocarcinoma, Metastasis