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Korean Journal of Obstetrics & Gynecology 1997;40(1):66-70.
Published online January 1, 2001.
A Study of a Molecular Variant of Angiotensinogen Associated with Korean Pregnancy-Induced Hypertension.
Young Tae Kim, Pyong Sahm Ku, Min Soo Lee
Abstract
Pregnancy-induced hypertension(PIH) is one of the major causes of maternal, fetal and neonatal morbidity and mortality. Although many causes are encountered, etiology of PIH is still unknown. A molecular variant of angiotensinogen, M235T, reported to be linked with essential hypertension and PIH. This study was to evaluate the molecular variation of angiotensinogen in Korean pregnancy-induced hypertension. Our results did not provide any definite relation with the molecular variant of angiotensinase, M235T, and Korean PIH.
Key Words: PCR, Angiotensinogen ( M235T ), Pregnancy-induced hypertension


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