A Case of Cyclopia Delivered from a Diabetic Mother.

Chang, Yuk Jea; Koh, Kyung Sim; Lee, Won Ki; Park, Choong Hak

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Obstet Gynecol Sci > Volume 40(3); 1997 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 1997;40(3):645-651.
Published online January 1, 2001.

A Case of Cyclopia Delivered from a Diabetic Mother.

Yuk Jea Chang, Kyung Sim Koh, Won Ki Lee, Choong Hak Park

Department of Obstetrics and Gynecology, College of Medicine, Dankook University, Cheonan, Korea.

Abstract

Cyclopia is a rare congenital fetal anomaly, characterized by a single median eye and a grotesquily shaped nose(proboscis) that arises from the supraorbital area. It is consistently associated with serere holoprosencephaly, which is the failure of cleavage of the prosencephalon with a deficite in the midiline facial development. Holoprosencepphaly occurs in as many as 1 to 2 % of diabetic mothers. A case of cyclopia delivered from a diabetic mother is presented with a brief review of literatures.

Key Words: Cyclopia, Diabetes, Holoprosencephaly, Proboscis

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