Treatment of Cervical Pregnancy with Methotrexate.

Bang, Young Tae; Yoo, Dal Young; Sun, Yun Soo; Jung, Hwan Bu; Kim, Dae Young; Kang, Jae Yeol

Case Report

Korean Journal of Obstetrics & Gynecology 1997;40(7):1546-1550.
Published online January 1, 2001.

Treatment of Cervical Pregnancy with Methotrexate.

Young Tae Bang, Dal Young Yoo, Yun Soo Sun, Hwan Bu Jung, Dae Young Kim, Jae Yeol Kang

Department of Obstetrics and Gynecology, Eul-ji General Hopspital, Seoul, Korea.

Abstract

Cervical pregnancy is one of most rare form of ectopic pregancy in which the blastocyst implants within the cervical canal below the internal os of uterine cervix. Most cervical pregnancy result in early spontaneous abortion, complicated by severe hemorrhage frm the eroded blood vessels within the cervix. Because of fear of rofuse hemorrhage, abdominal hysterectomy has been historically considered the standard therapy. However, a number of new therapies have been aimed at uterine preservation, conservative treatment is highly desirable for young women who want to be pregnancy in the future. Methotrexate has been utilized recently for the successful management of tubal, interstitial, and cervical ectopic gestations. We report a case of a cervical preganncy that was successfully managed with methotrexate and leucovorine.

Key Words: Cervical pregnancy, methotrexate, Leucovorine