| A Study of Clinical Parameters Influencing Human Zona Pellucida Thickness. |
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Hyung Jin Park, Hyuck Dong Han, Min Hong, Sang Won Han, In Bai Chung, Young Jin Lee |
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Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Wonju, Korea. |
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| Abstract |
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The purpose of present study was to assess which parameters influence human oocyte zona pellucida(ZP). Zone pellucida thickness was evaluated in 124 oocytes of 16 cycles IVF-ET with intracytoplasmic sperm injection(ICSI) between July 1995 and October 1995 at the department of obstetrics and Gynecology, Yonsei university, Wonju Christian Hospital. The zone pullucida thickness was 17.7+/-2.0micronm(mean+/-SD) for 107 metaphase II oocy- tes. The zona pullucida thickness was singinficantly different according to maximum estr- adiol(E2) value ; The mean thickness of Zona pellucida was thinner below 2000 pg/ml of E2 value than that above 2001 pg/ml of E2 value(p<0.05). And when the metaphase II oocytes was cultured for 3 days, the mean thickness of Zona pellucida was thinner than that of metaphase II oocytes whether fertilization or not(p<0.01, p<0.03). But the Zona pellucida thickness was not significantly different from the age of women and the oocyte maturation status(p>0.05). |
| Key Words:
Zona pellucida thickness, Intracytoplasmic sperm injection, In vitro fertilization and embryo transfer |
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