Factors affecting reproductive outcome of hysteroscopic adhesiolysis for intrauterine adhesion: Live-birth rate after surgery.

Han, Woo Suk; Kim, Min Kyoung; Im, Seung Yeon; Park, Won I

doi:2012.55.10.707

Obstet Gynecol Sci > Volume 55(10); 2012 > Article

Original Article

Korean Journal of Obstetrics & Gynecology 2012;55(10):707-712.
DOI: https://doi.org/10.5468/KJOG.2012.55.10.707 Published online October 10, 2012.

Factors affecting reproductive outcome of hysteroscopic adhesiolysis for intrauterine adhesion: Live-birth rate after surgery.

Woo Suk Han, Min Kyoung Kim, Seung Yeon Im, Won I Park

Department of Obstetrics and Gynecology, Eulji University School of Medicine, Seoul, Korea. pwi3110@eulji.ac.kr

Abstract

OBJECTIVE
The purpose of this study is to assess the impact of various factors of hysteroscopic lysis of intrauterine adhesion on live-birth rate after surgery. METHODS: Medical records of 54 patients suffering from infertility or recurrent spontaneous abortion were retrospectively analyzed. The independent variables were degree of intrauterine adhesion, surgical technique, use of intrauterine Foley catheter, insertion of intrauterine device, and dose of postoperative estradiol. Multivariate analysis as well as univariate analysis was performed. RESULTS: Among the 54 patients, 17 patients gave live-birth. The degree of intrauterine adhesion was found to be a sole factor affecting the live-birth rate by univariate and multivariate analysis. The mechanical dissection with scissors had been resulted a higher live-birth rate against resectoscopic electrosurgery, but the difference was not statistically significant. CONCLUSION: The degree of intrauterine adhesion is the most important factor affecting the live-birth. The uses of intrauterine Foley catheter, insertion of intrauterine device and dose of postoperative estradiol have little impact.

Key Words: Asherman's syndrome, Adhesiolysis, Hysteroscopy, Reproductive outcome