Small cell carcinoma, hypercalcemic type of the ovary.

Kim, Su Seon; Seo, Young Jin; Kim, Mi Jung; Eom, Hye Mi; Jeong, Eun Jeong; Byun, Jung Mi; Kim, Young Nam; Lee, Kyoung Bok; Sung, Moon Su; Kim, Ki Tae; Jeong, Dae Hoon

doi:2012.55.12.1015

Case Report

Korean Journal of Obstetrics & Gynecology 2012;55(12):1015-1019.
DOI: https://doi.org/10.5468/KJOG.2012.55.12.1015 Published online December 18, 2012.

Small cell carcinoma, hypercalcemic type of the ovary.

Su Seon Kim, Young Jin Seo, Mi Jung Kim, Hye Mi Eom, Eun Jeong Jeong, Jung Mi Byun, Young Nam Kim, Kyoung Bok Lee, Moon Su Sung, Ki Tae Kim, Dae Hoon Jeong

¹Department of Obstetrics and Gynecology, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea. obgynjeong@hanmail.net
²Paik Institute for Clinical Research, Inje University, Busan, Korea.

Abstract

The patient was a 22-year-old woman, who presented with abdominal pain and palpable huge mass. The initial investigation by ultrasound examination showed a huge size heterogenous soild mass and then magnetic resonance imaging presented multilobulated, huge solid mass (16x13 cm) with heterogenous enhancement in left ovary. Serum calcium level was slightly elevated (10.6 mg/dL, normal less than 10.4 mg/dL) and cancer antigen 125 level was normal. She underwent a laparotomy and left salpingo-ophorectomy. Grossly, ovary consists of yellowish solid portion but not cystic portion and outer capsule was ruptured focally. The pathologic finding, including immunohistochemical finding, confirmed small cell carcinoma, hypercalcemic type from ovary. Now, She has been treated with adjuvant chemotherapy (cisplatin, adriamycin, etoposide, cyclophophamide). We report this case with brief review of literature.

Key Words: Ovarian cancer, Small cell carcinoma, Hypercalcemic type