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Obstet Gynecol Sci > Volume 55(12); 2012 > Article
Korean Journal of Obstetrics & Gynecology 2012;55(12):1035-1038.
DOI: https://doi.org/10.5468/KJOG.2012.55.12.1035    Published online December 18, 2012.
A case of acanthosis nigricans on vulvar area in menopausal woman with diabetes.
Jeong Won Oh, Ji Yeong Kim, Yun Sook Kim, Chang Jin Kim
1Department of Obstetrics and Gynecology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea. drsook@schmc.ac.kr
2Department of Pathology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Korea.
Abstract
Acanthosis nigricans (AN) is a dermatopathy with a distinctive appearance that facilitates its diagnosis. Although an external condition, it is associated with a wide variety of less obvious internal conditions, either benign or malignant. Insulin resistance figures prominently in its benign associations and plays a primary role in its development. The development of AN rarely requires treatment, although the underlying condition usually does. AN and insulin resistance are found frequently in obese and hyperandrogenic women. The vulva is the most likely place to find this marker. We experienced a case of AN with 71-year obese menopausal woman with diabetes who presented with itching sensation on vulvar area. AN was revealed on pathology and acitretin, control of blood glucose, and weight reduction were used. So we report it with a brief review of literatures.
Key Words: Acanthosis nigricans, Diabetes mellitus, Vulva


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