A Novel, Balanced Translocation t ( 7 ; 10 ) ( q22 ; q26 ) in a Couple with Repeated Spontaneous Abortion.

Suh, T K; Sohn, S H; Ryu, E K; Jeon, B G; Lee, E S; Han, Y; Moon, J S; Kim, K C

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Original Article

Korean Journal of Obstetrics & Gynecology 1998;41(2):636-641.
Published online January 1, 2001.

A Novel, Balanced Translocation t ( 7 ; 10 ) ( q22 ; q26 ) in a Couple with Repeated Spontaneous Abortion.

T K Suh, S H Sohn, E K Ryu, B G Jeon, E S Lee, Y Han, J S Moon, K C Kim

Abstract

Chromosomal abnormality is one of the main causes for the repeated spontaneous abortion. A 31-year-old patient, otherwise normal woman who had experienced three consecutive miscarriage were karyotyped using peripheral blood cells. The patient has been found to have a novel, balanced translocation, with a formal karyotype of 46,XX,der (7)t (7;10) (q22;q26). The present result suggests that chromosomal analysis may be necessary for diagnosing the couples experiencing repeated spontaneous abortion.

Key Words: Spontaneous abortion, Chromosome, Translocation

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