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Korean Journal of Obstetrics & Gynecology 1998;41(8):2241-2245.
Published online January 1, 2001.
A Case of Diffuse Malignant Mesothelioma of the Peritoneum.
S Kim, Y S Shin, Y S Seo, Y S Park, S L Nam, K S Seo
Abstract
Primary malignant mesothelioma of the peritoneum is a rare condition(annual incidence: 1~2 cases per million in the general population). A case of diffuse malignant mesothelioma of the peritoneum of a 54-year-old woman is reported. After laparotomy the patient was treated with intraperitoneal chemotherapy with cisplatin (100 mg), postoperative chemotherapy (6 cycles) with carboplatine (350 mg/m2), and cyclophosphamide (750 mg/m2). In the second-look operation, malignant mesothelioma was as minute nodules at the site of adhesion. So she had further treated with combination chemotherapy using cyclophamide (500 mg/m2) and pinorubicin (40mg/m2), and continude follow up of the CA 125 levels. The patient it still alive and the serum CA 125 level showed a close relation with the reponse to treatment (Surgery and chemotherapy). On the basis of the data from literature, we briefly review the epidemiology, diagnosis, and treatment of malignant peritoneal mesothelioma.


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