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Korean Journal of Obstetrics & Gynecology 1998;41(9):2363-2369.
Published online January 1, 2001.
A Retrospective Study for Clinical Characteristics of the Patients with Recurrent Cervical Cancer.
B S Kim, C B Yoon, J H Sung, E H Lee, S Y Ryu, J H Kim, B G Kim, S Y Park, E D Rhee, K H Lee
This study was performed to evaluate the survival and clinical characteristics of recurrent cervical carcinoma following initial treatment. METHODS: From Jan. 1994 to Dec. 1994, total 79 patients were identified to have recurrence by physical examination, Pap smear, radiologic studies (chest PA, CT/MRI) or/and PCNA (percutaneous needle aspiration cytology). Their medical records and cytologic slides were reviewed. The information about survival and disease status was obtained from the last follow-up date in medical records or from interview via telephone. RESULTS: For the initial FIGO stage of recurrent cervical carcinoma, 18 patients (22.8%) were stage I ; 38 patients (48.1%), stage II; 21 patients (26.6%), stage III; 2 patients (2.5%), stage IV. The recurrent sites in patients with recurrent carcinoma were classified into central pelvic, lateral pelvic, and distant metastasis, and 24 patients (30.4%) showed central pelvic recurrence; 7 patients (8.9%), lateral pelvic recurrence; 48 patients (60.7%), distant metastasis. The most frequent metastatic site was paraaortic LN. For the detection of recurrent tumor, 33 of 79 patients (41.0%) were detected by symtoms and signs; 12 patients (17.0%), by Pap smear; 3 patients (3.1%), by chest PA; 16 patients (20.0%), by routine CT or MRI; 15 patients (18.9%), by PCNA. In these patients, the intervals from completion of initial treatment to recurrence were as follows: within 12 months, 15 patients (18.9%); from 12 months to 24 months, 31 patients (39.3%); from 24 to 36 months, 11 patients (13.9%); above 36 months, 22 patients (27.9%). The median survival of the patients studied was 38 months from the time of the diagnosis of recurrence. CONCLUSION: These results suggested that the regular follow-up at least 3 years should be made because more than 3/4 of the recurrence developed within 3 years. In addition,the routine diagnostic work-up to detect distant metastasis should be included at appropriate interval in this period. The strategy may improve the survival of the patients with recurrent cervical cancer.
Key Words: Recurrent cervical cancer, Recurrent fattern, Survival, Prognostic factor, follow-up

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