A Case of metastatic choriocarcinoma diagnosed at 34th week of pregnancy.

Song, Chi Hun; Jung, Su Mi; Yang, Won Gyu; Park, Jong Ho; Park, Won Il; Shin, Jung Whan; Joo, Jong Eun

Case Report

Korean Journal of Obstetrics & Gynecology 1999;42(1):198-202.
Published online January 1, 2001.

A Case of metastatic choriocarcinoma diagnosed at 34th week of pregnancy.

Chi Hun Song, Su Mi Jung, Won Gyu Yang, Jong Ho Park, Won Il Park, Jung Whan Shin, Jong Eun Joo

Abstract

Choriocarcinoma associated with a normal pregnancy is rare. Especially, choriocarcinoma coexistent with a viable pregnancy is even rarer and commonly presents with widespread metastatic disease. We experienced a patient at 34th week of pregnancy with dyspnea and sputum production due to pulmonary metastasis of choriocarcinoma. The serum B-hCG level was extremely elevated and the placenta had multifocal choriocarcinoma. After vaginal delivery, the patient was successfully treated with combination chemotherapy (EMA-CO). The patient is receiving follow up with monthly measurement of hCG values. We report one case of metastatic choriocarcinoma with viable pregnancy with review of literature.

Key Words: Metastatic Choriocarcinoma, Normal pregnancy