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Korean Journal of Obstetrics & Gynecology 1999;42(3):646-650.
Published online January 1, 2001.
A Case of Congenital Diaphragmatic Hernia that Occurred Following In Vitro Fertilization and Embryo Transfer.
Hyung Sik Chu, Hee Dong Chae, Chung Hoon Kim, Yoon Seok Chang, Jong Pyo Lee, Eun Hee Kang, Byung Moon Kang
Congenital diaphragmatic hernia (CDH) is caused by a failure of fusion of the muscular diaphragm and results in herniation of abdominal viscera into the thorax, It occurs in appoximately 1 in 2,200 to 5,000 live births, and most cases are probably multifactorial, but they can be also associated with chromosomal abenation. Due to the improvement of sonography, it can be diagnosed more accurately. However, the mortality associated with CDH is extremely high. It is well known that the incidence of congenital anomaly in infants after in vitro fertilization and embryo transfer (IVF-ET) is not increased copared with that of general population, and CDH that occurred following IVF-ET has not been reported. A case of CDH that occurred following IVF-ET is presented with brief review of literatures.
Key Words: Congenital diaphragmatic hernia (CDH), In vitro fertilization and embryo transfer (IVF-ET)

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