| Preliminary Results from a Case-Control Study on Risk Factors of Mental Retardation. |
|
K S Ko, J K Jun, J Choi, D Y Hwang, Y M Choi, S Y Moon |
1Dankook University, Cheonan.
2Institute of Reproductive Medicine and Population, Medical research Center, Seoul National University.
3Seoul Municipal Boramae Hospital.
4Hamchoon Institute of Fertility & Genetics, Hamchoon Women`s Clinic, Seoul, Korea. |
|
|
| Abstract |
OBJECTIVE
Prenatal and environmental factors for mental retardation were not clearly identified in Korea. The objective of our study is to determine risk factors of mental retardation and to give informations for further large epidemiologic study. METHODS: Using a case-control study design, 88 children with mental retardation as cases and 222 children without mental retardation as controls were selected and their mothers were asked about prenatal and environmental risk factors by questionnaires. For comparison of continuous variables we used Student t-test and for comparison of frequencies Chi-square test. Logistic regression was used for analysing the odds ratios and 95% confidence intervals for evaluating risk factors of mental retardation. RESULTS: Risk factors, which showed positive association with mental retardation, were inadequate maternal weight gain, low matenal and paternal education level, inappropriate food intakes during pregnancy, unstable marital status, delivery of first baby, low birth weight infant and medication during pregnancy. Some limitations of this study were also mentioned. CONCLUSION: Some risk factors of mental retardations were determined and gave us useful informations for further epidemiologic studies. |
| Key Words:
Mental retardation, risk factors, case-control study |
|
Full text via DOI
Download Citation
