Diagnostic Significance of Serum Tumor Markers  in Paitents with Ovarian Tumors.

Shin, Kwang Sik; Kim, Seok Mo; Choi, Ho Sun; Byun, Ji Soo

Search: Korean J Obstet Gynecol Search

CLOSE

Original Article

Korean Journal of Obstetrics & Gynecology 2000;43(4):715-720.
Published online January 1, 2001.

Diagnostic Significance of Serum Tumor Markers in Paitents with Ovarian Tumors.

Kwang Sik Shin, Seok Mo Kim, Ho Sun Choi, Ji Soo Byun

Abstract

OBJECTIVE
This study was designed to evaluate the efficiency of tumor markers level for early diagnosis of ovarian malignancy and for differentiation between benign and malignant ovarian tumors. MATERIALS AND METHODS: We determined preoperative serum tumor markers level in patients who were going to have an operation due to ovarian tumor in OB & GY Dept. of Chonnam University Hospital from April 1993 to September 1999. RESULTS: 1) The average values of serum tumor markers in patients with malingnant ovarian tumors were statistically higher than those of benign ovarian tumors. among malignant ovarian tumors, positive rate of all serum tumor markers was highest in epithelial ovarian carcinoma group. and among ovarian tumor markers, and positive rate of CA 125 was highest in epithelial ovarian carcinoma. 2) Dermoid cyst and endometioma were correlated to CA 19-9, CA 125 levels respectively. for malignant tumors, mucinous ovarian adenocarcinoma and non-mucinous ovarian adenocarcinoma were CA 19-9, CA 125 levels respectively. 3) Among ovarian tumor markers, CA 125 was the most in sensitivity and CA 72-4 was the most in specificity and diagnostic efficiency. 4) For postmenopausal women with ovarian tumors, elevated levels of at least one of the 4 tumor markers were present in the serum in 85.7% of the women who developed cancer, 62.5% of women with borderline, 27.8% of women with benign ovarian tumors. Conclusion; It is suggested that determination of serum tumor markers in patient suspected of ovarian tumor may be helpful to clinician for early diagnosis, differentiation between malignant and benign ovarian tumors.

Key Words: Tumor Markers, Ovarian Tumors

TOOLS

Full text via DOI
Download Citation

Share :

METRICS

782 View
10 Download

Related articles in Obstet Gynecol Sci

Prognostic significance of tumor laterality in advanced ovarian cancer2021 November;64(6)

Clinical significance of CA 125 in epithelial ovarian carcinoma.1992 January;35(1)

The efficacy of tumor markers SCC Ag, CEA and CA-125 in patients with cervical cancer.1992 April;35(4)

Immunohistochemical study on ovaries in patient with prenature ovarian failure.1992 August;35(8)

Clinical significance of second look laparotomy in ovarian cancer patients.1992 September;35(9)

ABOUT

ARTICLE & TOPICS

Article category

Browse all articles >

Topics

Browse all articles >

BROWSE ARTICLES

POLICY

FOR CONTRIBUTORS

Editorial Office: 4th Floor, 36 Gangnam-daero 132-gil, Gangnam-gu, Seoul 06044, Korea.
Tel: +82-2-2266-7238 Fax: +82-2-3445-2440 E-mail: journal@ogscience.org