Cases with Endometrial Polyp and Endocervical Polyp Associated With Tamoxifen Use.

Choe, Byung Hoon; Choi, Eun Kyoung; Kim, Young Tae; Kim, Jae Wook; Park, Byung Woo

Case Report

Korean Journal of Obstetrics & Gynecology 2000;43(4):725-730.
Published online January 1, 2001.

Cases with Endometrial Polyp and Endocervical Polyp Associated With Tamoxifen Use.

Byung Hoon Choe, Eun Kyoung Choi, Young Tae Kim, Jae Wook Kim, Byung Woo Park

Abstract

Tamoxifen is a nonsteroidal triphenylethylene delivative that has been widely used in the treatment of breast cancer. tamoxifen is indicated for the adjuvant treatment of breast cancer in women following total mastectomy or segmental mastectomy, breast irradiation and chemotherapy. tamoxifen has been shown to have significant benificial effect in the treatment of breast cancer patient as hormonal therapy. However ,there is mounting evidence that tamoxifen may affect other hormon sensitive organs, including the uterus and ovaries. An increased risk of endometrial polyps, endometrial hyperplasia and adenocarcinoma has been reported in tamoxifen treated women. We have met cases of endometrial polyp and endocervical polyp which were associated with tamoxifen use, after modified radical mastectomy for infilterating ductal carcinoma of breast . So we report these cases with the brief review of literatures.

Key Words: endometrial polyp, endocervical polyp, tamoxifen