A Case of Choriocarcinoma following Term Pregnancy.

Lee, Chun Bae; Jang, Youn Choo; Lee, Jin Ho; Lee, Jung Seok; Lee, Ji Yeon; Lee, Shin Ae; Kim, Jong Woo

Case Report

Korean Journal of Obstetrics & Gynecology 2000;43(7):1269-1272.
Published online January 1, 2001.

A Case of Choriocarcinoma following Term Pregnancy.

Chun Bae Lee, Youn Choo Jang, Jin Ho Lee, Jung Seok Lee, Ji Yeon Lee, Shin Ae Lee, Jong Woo Kim

Abstract

Gestational trophoblastic tumor became one of the curable disease due to the development of chemotherapy, appropriate follow up of beta- human chorionic gonadotropin and others. But metastatic trophoblastic tumor still shows high mortality rate because of resistance to the chemotherapy and large tumor burden.One of the important prognostic factors determining the prognosis of gestational trophoblastic tumor is antecedent pregnancy, which affects the response to therapy. Choriocarcinoma following term pregnancy is rare one with the incidence of one per 160,000 pregnancies in United States and the prognosis is poor because of late diagnosis and combined high risk prognostic factors.We present a choriocarcinoma following term pregnancy that required emergency total abdominal hysterectomy due to profuse bleeding with brief review of literatures.

Key Words: Choriocarcinoma, term pregnancy, profuse bleeding