A Case of Adenoma Malignum at the Uterine Cervix.

Lee, Sang Hoon; Park, Sung Yong; Kim, Sang Jin; Cha, Moon Suk; Kim, Hyun Ho; Rha, Sur Hee; Jung, Jin Sook

Case Report

Korean Journal of Obstetrics & Gynecology 2000;43(11):2106-2106.
Published online January 1, 2001.

A Case of Adenoma Malignum at the Uterine Cervix.

Sang Hoon Lee, Sung Yong Park, Sang Jin Kim, Moon Suk Cha, Hyun Ho Kim, Sur Hee Rha, Jin Sook Jung

Abstract

We report one case of adenoma malignum of the cervix. Adenoma malignum is an extremely well-differentiated form of adenocarcinoma in which the branching glandular pattern strongly simulates that of the normal endocervical glands. This term has been used to describe a very well-differentiated adenocarcinoma characterized histologically by distorted and architecturally irregular endocervical glands which penetrate deeply into the wall of the cervix, but with minimal and focal evidence of glandular cell stratification, anaplasia, or mitotic activity. Despite this innocuous histologic appearance, these tumors have classically been thought to be clinically highly malignant, with an almost invariably rapid lethal outcome. The diagnosis of minimal deviation adenocarcinoma (adenoma malignum) of the endocervix may be difficult. The diagnosis was adenocarcinoma on the Pap Smear treatment has been hysterectomy.

Key Words: Adenoma Malignum