A Case of Embryonal Rhabdomyosarcoma of the Uterine Cervix in a 31 Year Old Woman.

Jang, Jin Bum; Kang, Suk Ho; Kim, Young Tae; Kim, Jae Wook; No, Tae Woong; Kim, Ho Geun

Obstet Gynecol Sci > Volume 44(1); 2001 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 2001;44(1):202-207.
Published online: January 1, 2001

A Case of Embryonal Rhabdomyosarcoma of the Uterine Cervix in a 31 Year Old Woman.

Jin Bum Jang, Suk Ho Kang, Young Tae Kim, Jae Wook Kim, Tae Woong No, Ho Geun Kim

¹Department of Obstetrics and Gynecology, Yonsei University College of Medicine, Seoul, Korea.
²Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Rhabdomyosarcoma is the most common soft tissue sarcoma in childhood and young adult. Rhabdomyosarcoma can be classified into one of four type; embryonal, alveolar, pleomorphic, undifferentiated. Embryonal rhabdomyosarcomas of the female genital tract are rare, malignant tumors derived from primitive myogenic precursor and generally occur during infancy and childhood. About twenty percent of rhabdomyosarcoma arise in the genitourinary tract, with slightly more than half being embryonal rhabdomyosarcoma. Vaginal primaries are 5-times more common than cervical primaries. Overall, cervical tumor may predominate in adolescent. In perimenopausal women, the uterus is the most common site of rhabdomyosarcoma. The management of rhabdomyosarcoma of genitourinary tract has changed slowly from pelvic exenteration without adjuvant therapy to neoadjuvant chemotherapy followed by less radical surgery and postoperative radiation. Embryonal rhabdomyosarcomas originates in the uterine cervix are extremely rare especially in the thirties. So, little information is available regarding its prognosis and therapy. We present a case of a woman 31 years old with embryonal rhabdomyosarcoma of the uterine cervix with a review of a literature.

Keywords: Embryonal rhabdomyosarcoma; Uterine cervix