Clinical Study of Intrauterine Insemination following Clomiphene/hMG Combined Superovulation in Infertile Couples.

Yang, Hoe Saeng; Kim, Jong Ho; Sim, Jae Cheol

Original Article

Korean Journal of Obstetrics & Gynecology 2001;44(2):342-347.
Published online February 1, 2001.

Clinical Study of Intrauterine Insemination following Clomiphene/hMG Combined Superovulation in Infertile Couples.

Hoe Saeng Yang, Jong Ho Kim, Jae Cheol Sim

Department of obstetrics & Gynecology, College of Medicine, Dongguk University, Korea.

Abstract

OBJECTIVES
To determine the effect of clomiphene/hMG combined superovulation with intrauterine insemination on pregnancy outcomes. MATERIALS AND METHODS: Eighty-one cycles of clomiphene/hMG combined superovulation with intrauterine insemination in forty-three infertile couples were analysed retrospectively. RESULTS: The overall pregnancy rate was 39.5% per patient and 20.9% per cycle. Each pregnancy rate of infertility due to ovulatory dysfunction, unexplained infertility and endometriosis was 43.8%, 40.0%, and 25.0% per patient respectively. CONCLUSIONS: Clomiphene/hMG superovulation with intrauterine insemination is a simple, cost effective and safe treatment modality in the management of infertility, and may improve a pregnancy rate.

Key Words: Clomiphene/hMG, Infertility, Superovulation, Intrauterine Insemination