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Korean Journal of Obstetrics & Gynecology 2001;44(8):1419-1425.
Published online August 1, 2001.
The Clinical Significance and The Optimal Management of Atypical Squamous Cells of Undetermined Significance in Cervical Smears.
Jung Mook Yoon, Sang Eun Lee, Tae Yul Hwang, Kyung Min Song, Pyo Hong, Soo Kee Min, Seong Ook Hwang, Joon Mee Kim, Seung Kwon Koh, Sook Cho, Woo Young Lee
1Department of Obstetrics and Gynecology, InHa Hospital, College of Medicine, InHa University, Sung-Nam, Korea.
2Department of Pathology, InHa Hospital, College of Medicine, InHa University, Sung-Nam, Korea.
To evaluate the clinical significance and the optimal management of atypical squamous cells of undetermined significance (ASCUS) in Papanicolaou cervical smears. METHOD: This study included 25380 cases of cervical Pap smears received from January 1995 to June 2000 by the Department of Obstetrics & Gynecology, Inha Hospital, Medical College, the Inha University. Retrospective review was done on 384 cases of ASCUS. RESULT: ASCUS and squamous intraepithelial lesions (SIL) were diagnosed in 384 cases (1.5%), and 311 cases (1.1%), respectively. The ratio of ASCUS to SIL was 1.2. Colposcopic directed biopsies revealed 14 cases (14.1%) of low grade SIL (LSIL), 21 cases (21.2%) of high grade SIL (HSIL), and 2 cases (2.0%) of squamous cell carcinoma. CONCLUSION: The immediate colposcopy with biopsy in women with ASCUS may decrease follow-up visits for Pap testing, reduce patient anxiety, minimize the loss of high risk cases during follow-up and lower medicolegal litigation. The early colposcopy may be the method of choice for follow-up in women with ASCUS in Korea.
Key Words: Atypical squamous cells of undetermined significance, cervical smears

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