Korean J Obstet Gynecol Search


Korean Journal of Obstetrics & Gynecology 2001;44(9):1609-1616.
Published online September 1, 2001.
Multi-center Study for Birth Defects Monitoring Systems in Korea.
Kyung Sim Koh, Ahm Kim, Soon Ha Yang, Jung Yeol Han, Eun Sung Kim, Moon Young Kim, Jae Hyug Yang, Kyo Hoon Park, Sung Soo Kim, Bo Hyun Yoon
1Dankook University Hospital.
2Asan Medical Center.
3Samsung Medical Center.
4Samsung Cheil Hospital.
5Sanggye Baik Hospital.
6Bombit Women's Hospital.
7Seoul National University Hospital.
Our aim was to establish a multi-center birth defects monitoring system for evaluating the prevalence and serial occurrence of birth defects in Korea. METHODS: Seven centers participated in this monitoring system. Trained nurses actively collected the 42,015 delivery records obtained from delivery units and pediatric clinics in the participating hospitals every month. RESULTS: We observed 722 birth defects among 42,015 births including live births and stillbirths. The prevalence of birth defect was 1.7%. About one thirds of birth defects were terminated. The most frequent congenital anomalies were cleft lip and Down syndrome. The highest proportion of birth defects was 20.1% in urogenital system. The proportion of birth defects in cardiovascular system and gastrointestinal system were 17.1% and 14.1% respectively. Chromosomal anomalies and genetic syndromes represent 13.4% and 3.3% among birth defects respectively. Among chromosomal anomalies Down syndrome was at the first rank. CONCLUSION: We could establish multi-center active monitoring system for birth defects successfully. To check serial occurrence of birth defects, it is necessary to increase participating hospitals and to launch the nationwide multi-center study.
Key Words: Birth defects monitoring systems, congenital anomalies, Down syndrome, cleft lip

Article category

Browse all articles >


Browse all articles >

Editorial Office
4th Floor, 36 Gangnam-daero 132-gil, Gangnam-gu, Seoul 06044, Korea.
Tel: +82-2-2266-7238    Fax: +82-2-3445-2440    E-mail: journal@ogscience.org                

Copyright © 2024 by Korean Society of Obstetrics and Gynecology.

Developed in M2PI

Close layer
prev next