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Korean Journal of Obstetrics & Gynecology 2001;44(11):2036-2039.
Published online November 1, 2001.
Twin pregnancies conceived by In-vitro fertilization compared with normally conceived twin pregnancies: Maternal and neonatal outcome.
Byung Wook Kim, Min Hong, Geon Young Lee, Jeong Yel Lee, Jun Hee Lee, In Bai Chung, Young Jin Lee
Department of Obstetrics and Gynecology, Yonsei University Wonju college of Medicine, Wonju, Korea.
Abstract
OBJECTIVE
To compare the obstetric complications and perinatal outcomes of twin pregnancies conceived by In Vitro Fertilization and Embryo Transfer to twin pregnancies conceived naturally. METHODS: Maternal and neonatal data were reviewed for all twin pregnancies. All twin pregnancies (n=116) were divided into IVF twin pregnancyes group (n=43) and naturally conceived twin pregnancyes (n=72). The obstetric and perinatal outcomes were compared and analysed. Statistical analysis was performed using student's t-test, x2 test, and Fisher exact test. Statistical significance was defined as p<0.05. RESULTS: There were no significant differences in maternal age and gestational age between two groups but nulliparity was higher in IVF-ET twin group than naturally conceived twin group. Also no differences of obstetrics and perinatal outcomes were seen between two groups. CONCLUSION: Although twin pregnancies following IVF-ET are more likely to result in bad prognosis, in this study obstetric and perinatal outcomes are comparable to those of naturally conceived twin pregnancies.
Key Words: Twin pregnancy, IVF-ET, Obsteric and perinatal outcome


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