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Korean Journal of Obstetrics & Gynecology 2002;45(2):327-331.
Published online February 1, 2002.
A Case of Uterine Rupture in Pregnancy Complicated with Myelodysplastic Syndrome.
Byeong Do Lim, Hyuk Woo Lee, Sung Hong Joo, Eui Sik Jung, Chang Seo Park, Sung Jin Cho
Department of Obstetrics and Gynecology, National Medical Center, Seoul, Korea.
Abstract
Myelodysplastic syndrome (MDS) is a relatively uncommon hematological disorder, charactedzed by cytopenia in the peripheral blood and normo-or hypercellularity in the bone marrow with morphological dysplastic change. Ineffective hematopoiesis leads to hematological failures in this syndrome. MDS is largeIy affected in older individuaIs with a median age of 60-75. It's association with pregnancy is even rarer. Although the exact incidence of MDS in pregancy is unknown, it is likely to be less than 1 per 100,000 pregnancies annually. Recently, we experienced a case of MDS presented initially during pregnancy in a 34-year-old primipara and managed with intensive hematologic support. Uerine rupture occurred in pregnancy complicated with MDS at 34 gestation weeks and a healthy infant was successfully delivered by Cesarean section. We report this case with a brief review of the literature.
Key Words: Myelodysplastic syndrome, Pregnancy, Uterine rupture


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