A Case of Antenatally Detected Schizencephaly.

Jeong, Bong Jin; Lee, Kee Su; Choong, Eui Jung; Hwang, Jin Seok; Kim, Young Hywan

Case Report

Korean Journal of Obstetrics & Gynecology 2002;45(3):529-532.
Published online March 1, 2002.

A Case of Antenatally Detected Schizencephaly.

Bong Jin Jeong, Kee Su Lee, Eui Jung Choong, Jin Seok Hwang, Young Hywan Kim

¹Department of Obstetrics and Gynecology, Dong-Gang Hospital, Ulsan, Korea.
²Department of Diagnostic Radiology, Dong-Gang Hospital, Ulsan, Korea.

Abstract

Schizencephaly is an unusual condition rarely detected antenatally. It is a neuronal migrational disorder consisting of clefts in the brain that communicate with the lateral ventricles. The etiology and the pathogenesis is not clearly estabilished. While some authors advocate a vascular insult with a secondary effect on brain development, others suggest a primary cerebral dysgenesis by genetic or acquired factors. The importance of making an accurate antenatal diagnosis is that the outcome for schizencephaly in considerably poor than for other causes of ventriculomegaly. Typical symtoms include seizures, mental retardation, spastic tetraplagia and blindness. We report a case of typeIIschizencephaly that was diagnosed antenatally in the third trimester with a brief reiew of literatures.

Key Words: Schizencephaly, Antenatal diagnosis