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Korean Journal of Obstetrics & Gynecology 2002;45(9):1485-1490.
Published online September 1, 2002.
Frequency of fetal anomaly and perinatal outcome in polyhydramnios.
Katherine Pak, Su Jung Kim, Ha Jung Lim, Eun Jeong Kim, Won Sik Lee, Min Jeong Oh, June Seek Choi, Hur Kuol, Sang Hee Jung, Hyun Kyong Ahn, Jung Yeol Han, Moon Young Kim, Hyun Mee Ryu, Kyu Hong Choi, Jae Hyug Yang
1Department of Obstetrics and Gynecology, Samsung Cheil Hospital and Women's Healthcare Center, Sungkyunkwan University School of Medicine, Korea.
2Department of Obstetrics and Gynecology, Korea University School of Medicine, Seoul, Korea.
To determine the frequency of fetal anomaly and perinatal outcome in pregnant women with polyhydramnios. METHODS: Ultrasound examinations from January 1998 to August 2001 were reviewed to identify 170 patients with singleton pregnancy which diagnosed polyhydramnios. Frequency of fetal anomaly and perinatal outcomes were compared with amniotic fluid index (AFI) 20.0-25.0 cm as group 1 and AFI >25.0 cm as group 2. RESULTS: The prevalence of polyhydramnios was 0.54% (170/31,358). The types of structural anomalies were gastrointestinal system (10/34, 29.4%), genitourinary system (9/34, 26.5%), central nervous system (CNS, 6/34, 17.7%), cardiovascular system (CVS, 3/34, 8.8%), neuromuscular system (2/34, 5.9%), respiratory system (1/34, 2.9%) and others (3/34, 8.8%). The structural anomaies between two groups were significantly different. The rate of cesarean section, low 5-min Apgar score (<7), large for gestational age (LGL, 95 percentile), Nursery Intensive Care Unit (NICU) visitation and perinatal death were not significantly different between two groups. CONCLUSION: The prevalence of fetal anomaly was 20% (34/170) and significantly different between two groups (p=0.0143). However, the perinatal outcome was not significantly different between two groups. CNS, gastrointestinal system and CVS anomalies were more frequent in group 2 (AFI>25.0 cm) and genitourinary system anomaly was dominant in group 1 (AFI 20.0-25.0 cm). Polyhydramnios (AFI>25.0 cm) indicated an increased risk of severe fetal anomaly.
Key Words: Polyhydramnios, Fetal anomaly, Perinatal outcome

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