A case of McCune-Albright syndrome.

Jeong, Sun Young; Song, Min Kyung; Lee, Jin Woo

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Korean Journal of Obstetrics & Gynecology 2003;46(1):184-187.
Published online January 1, 2003.

A case of McCune-Albright syndrome.

Sun Young Jeong, Min Kyung Song, Jin Woo Lee

Department of Obstetrics and Gynecology, College of Medicine, Catholic University, Seoul, Korea.

Abstract

McCune-Albright syndrome is a rare disease. It's triad is 1) precocious puberty, 2) fibrous dysplasia of bone and 3) caf-al-lait spots on skin. The cause is known as the mutation of subunit of G protein. Although there are some suggestions of treatment regimens including antiestrogen and GnRH agonist, at present, the accurate management is not known. We have experienced a case of McCune-Albright syndrome who has precocious puberty and fibrous dysplasia without caf-al-lait spot, and we present the case with a review of related literatures.

Key Words: McCune-Albright syndrome, precocious puberty, fibrous dysplasia, caf-al-lait spots, G-protein

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