A Case of Vulvar Glassy Cell Carcinoma.

Kim, Ji Hyun; Jun, Hyo Jeong; Je, Goo Hwa; Rha, Seo Hee; Kim, Dae Chul

Case Report

Korean Journal of Obstetrics & Gynecology 2003;46(4):838-841.
Published online April 1, 2003.

A Case of Vulvar Glassy Cell Carcinoma.

Ji Hyun Kim, Hyo Jeong Jun, Goo Hwa Je, Seo Hee Rha, Dae Chul Kim

¹Department of Obstetrics and Gynecology, Dong-A University College of Medicine, Busan, Korea.
²Department of Pathology, Dong-A University College of Medicine, Busan, Korea.

Abstract

Vulvar glassy cell carcinoma (GCC) is a very rare neoplasm. Although GCC is considered to be a poorly differentiated variant of adenosquamous carcinoma, its real nature is still debatable. We report a case of GCC of the vulva in a 53-year-old woman and review the literatures. The patient had bleeding from the lesion of the vulva and pelvic MRI revealed left inguinal lymph node enlargement. Histologically a cytoplasm of ground glass appearance was observed with a distinct cell wall and large nucleus containing prominent nucleoli. The clinical stage of the tumor was III as classified by the International Federation of Gynecology and Obstetrics (FIGO). She was treated by a left hemivulvectomy and bilateral inguinal lymphadenectomy and followed by external irradiation to the pelvis and left inguinal area. The patient was still alive without evidence of disease after 12 months treatment.

Key Words: Vulvar cancer, Glassy cell carcinoma