A Case of Papillary Serous Carcinoma of Endometrium.

Jo, Kweon Moon; Kim, Jae Won; Lim, Ji Eun; Hwang, Jong Ha; Kim, Hai Joong; Kim, Tak; Lee, Eung Seok; Shin, Jin Woo

Case Report

Korean Journal of Obstetrics & Gynecology 2003;46(6):1222-1226.
Published online June 1, 2003.

A Case of Papillary Serous Carcinoma of Endometrium.

Kweon Moon Jo, Jae Won Kim, Ji Eun Lim, Jong Ha Hwang, Hai Joong Kim, Tak Kim, Eung Seok Lee, Jin Woo Shin

Department of Obstetrics and Gynecology, College of Medicine, Korea University, Ansan, Korea.

Abstract

Uterine papillary serous carcinoma (UPSC) has been recognized as an aggresive tumor with early and deep myometrial invasion, frequent lympho-vascular space involvement, and a high relapse rate. It has also been shown that deep myometrial invasion cannot predict the risk of extrauterine disease. UPSC accounts for 2-10% of all endometrial cancer and generally occurs in postmenopausal women (mean age 66 years) who usually present with abnormal vaginal bleeding. Obesity, diabetes, hypertension, or a history of previous hormone replacement treatment, known as risk factors of endometrial cancer, are not usually seen in women with UPSC. In this paper, we present a case of uterine papillary serous carcinoma with obesity, hypertension, diabetes. The initial endometrial biopsy showed an endometrioid adenocarcinoma but the result of postoperative pathologic finding revealed UPSC with extension to less than half thickness of the muscle layer and involvement of pelvic lymph node.

Key Words: Uterine papillary serous carcinoma, Risk factors, Myometrial invasion, Endometrial biopsy, Lymph node involvement