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Korean Journal of Obstetrics & Gynecology 2003;46(7):1358-1362.
Published online July 1, 2003.
The Comparative Analysis of Cytology, Colposcopically Directed Biopsy and Final Histopathology in Diagnosis of Cervical Neoplasia.
Ho Ryong Kim, Hyung Ho Kim, Yea Young Chun, Jin Young Gu, Sun Woong Hong, Jin Gyu Sun, Kwang Soo Kee
Department of Obstetrics and Gynecology Kwangju Christian Hospital, Kwangju, Korea.
To investigate the necessity of colposcopically directed biopsy for more accurate detection of cervical neoplasm. METHODS: Cytology and colposcopically directed biopsy were performed in 114 patients and the patients were subsequently underwent conization or hysterectomy from January, 1998 to December, 2001. RESULTS: The complete diagnostic agreement of cytology with permanent biopsy was 57.9% (66 of 114) and the diagnostic agreement within one degree was 80.6% (92 of 114). The complete diagnostic agreement of colposcopically directed biopsy with permanent biopsy was 62.3% (71 of 114) and the diagnostic agreement within one degree was 85.1% (97 of 114). The difference between two tests was statistically significant (p<0.001). CONCLUSION: We concluded that colposcopically directed biopsy can reduce the false negative rate of cytology for screening test of cervical neoplasm. The difference between colposcopically directed biopsy and permanent biopsy was caused by inappropriate resection of the lesion and unskilled physician.
Key Words: Cytology, Colposcopically directed biopsy, Cervical neoplasia

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