A Case of Heterotopic Pregnancy after Ovulation Induction.

Chay, Doo Byung; Seo, Kyung; Kim, Cheong Mee; Lee, Dae Woo; Seo, Seok Kyo; Huh, Eun Ha; An, Jung Mi; Kim, Ki Whang; Hong, Soon Won

Case Report

Korean Journal of Obstetrics & Gynecology 2003;46(9):1832-1836.
Published online September 1, 2003.

A Case of Heterotopic Pregnancy after Ovulation Induction.

Doo Byung Chay, Kyung Seo, Cheong Mee Kim, Dae Woo Lee, Seok Kyo Seo, Eun Ha Huh, Jung Mi An, Ki Whang Kim, Soon Won Hong

¹Department of Obstetrics and Gynecology, Yongdong Severance Hospital, Yonsei University, College of Medicine, Seoul, Korea.
²Department of Diagnostic Radiology, Yongdong Severance Hospital, Yonsei University, College of Medicine, Seoul, Korea.
³Department of Pathology, Yongdong Severance Hospital, Yonsei University, College of Medicine, Seoul, Korea.

Abstract

Heterotopic pregnancy, simultaneous intrauterine and extrauterine pregnancy, classically was considered a exceedingly rare obstetrical phenomenon. But nowadays the natural incidence is increasing and especially in association with assisted reproductive technologies, such as use of variable methods for ovulation inductions, in-vitro fertilization and embryo transfer, and gamate intrafallopian transfer. In spite of the difficult early diagnosis, which is potentially dangerous to the mother and fetus, the maternal mortality, morbidity and fetal loss is low when the diagnosis is made in timely fashion and proper management is achieved. The presence of a intrauterine pregnancy dose not exclude the possibility of a extrauterine pregnancy, and in women associated with assisted reproductive technologies, the possibility of a heterotopic pregnancy should be considered. We report a case of a heterotopic pregnancy following ovulation induction and intrauterine insemination with brief review of literature.

Key Words: Heterotropic pregnancy, Assisted reproductive technologies, Ovulation induction, Clomiphene citrate use