A Case Diagnosed to Cushing's Syndrome Caused by Adrenal Cortical Adenoma during Pregnancy after Ovulation Induction.

Kim, Hyuk; Park, Cheol Hong; Choi, June; Choi, Eyn Young; Jeon, Young Mi; Kim, Su Kyoung; Shin, Jung Hwan; Hong, Seo Yoo

Obstet Gynecol Sci > Volume 46(11); 2003 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 2003;46(11):2270-2275.
Published online November 1, 2003.

A Case Diagnosed to Cushing's Syndrome Caused by Adrenal Cortical Adenoma during Pregnancy after Ovulation Induction.

Hyuk Kim, Cheol Hong Park, June Choi, Eyn Young Choi, Young Mi Jeon, Su Kyoung Kim, Jung Hwan Shin, Seo Yoo Hong

Department of Obstetrics and Gynecology, Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea.

Abstract

This woman was a secondary infertile patient with amenorrhea, hirsutism, and hyperprolactinemia due to excessive secretion of androgen. We had an impression that her disease was polycystic ovary syndrome, and she became pregnant after ovulation induction. Complications arised, such as hypertension, diabetes and pulmonary edema at 23rd week of pregnancy and physical findings of Cushing's syndrome were observed. Cushing's syndrome caused by adrenal cortical adenoma was diagnosed through endocrine and radiologic examination. We let her keep pregnancy through adjusting hypercorticolism with metyrapone to restrain abnormal steroidogenesis during pregnancy. After delivery, we carried out adrenalectomy through laparoscopic surgery and then can't find out any problem to be appeared to the mother and her neonate. We report this case with brief discussion.

Key Words: Cushing's syndrome, Pregnancy