A Case of Partial Hydatidiform Mole with a Coexistent Live Fetus.

Kim, Yoon Sook; Lee, Hae Hyeog; Kim, Hyeong Mun; Cho, In Sook; Kim, Tae Hee; Shim, Yil Ku; Nam, Kye Hyun; Lee, Kwon Hae; Park, Seong Jin; Koh, Eun Suk; Lee, Im Soon

Case Report

Korean Journal of Obstetrics & Gynecology 2003;46(12):2486-2491.
Published online December 1, 2003.

A Case of Partial Hydatidiform Mole with a Coexistent Live Fetus.

Yoon Sook Kim, Hae Hyeog Lee, Hyeong Mun Kim, In Sook Cho, Tae Hee Kim, Yil Ku Shim, Kye Hyun Nam, Kwon Hae Lee, Seong Jin Park, Eun Suk Koh, Im Soon Lee

¹Department of Obstetrics and Gynecology, Soonchunhyang University, Bucheon, Korea.
²Department of Radiology, Soonchunhyang University, Bucheon, Korea.
³Department of Pathology, Soonchunhyang University, Bucheon, Korea.

Abstract

Hydatidiform moles are generally separated into two classifications. Complete hydatidiform moles are characterized by cystic swelling of all villi, often pronounced diffuse trophoblastic hyperplasia, lack of fetal parts, all 46 chromosomes of paternal origin (androgenesis). Partial hydatidiform moles appear to be focal trophoblastic hyperplasia, a fetus or indications of previous fetal existence, 69 chromosomes. Hydatidiform mole with coexistent fetus is a very rare phenomenon, with an estimated incidence of 0.005 to 0.01 percent of all pregnancies and associated with a risk of persistent gestational trophoblastic tumor. Recently, hydatidiform moles with a fetus have become more common due to use of assisted reproductive technology. Most patients with hydatidiform mole and coexisting normal fetus must cautioned about the potential for risks of malignant change and severe medical complications, such as preeclampsia, hyperthyroidism and antepartum hemorrhage, that may necessitate prompt pregnancy termination. We experienced a case of partial hydatidiform mole with coexistent live fetus, which was diagnosed by ultrasonography at 15 gestational weeks. A brief reviews of related literature was done.

Key Words: Hydatidiform mole, Partial hydatidiform mole, Coexisting fetus, Trophoblastic disease