| Is Transient Bradycardia Following Cordocentesis Associated with Adverse Pregnancy Outcome?. |
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So Ra Ryu, Seung Hee Cha, Seung Youn Yu, June Seek Choi, Hyun Gyung An, Jung Yeol Han |
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Department of Obstetrics and Gynecology, Samsung Cheil Hospital and Women's Healthcare Center, College of Medicine, Sung Kyun Kwan University, Seoul, Korea. |
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| Abstract |
OBJECTIVE
To evaluate the association between transient bradycardia following cordocentesis and adverse pregnancy outcome. METHODS: 117 cordocentesis was performed at Samsung Cheil hospital and women's healthcare center, between January 1, 2000, and December 31, 2002. Clinically significant bradycardia was defined as a drop in the heart rate to less than 120 bpm. The adverse outcome included major anomaly, chromosomal abnormality, intrauterine growth restriction, preterm birth, and intrauterine fetal death. RESULTS: Bradycardia following cordocentesis was observed in 13 cases (11.1 per cent). The fetal heart rate before (149.2 +/- 0.7 bpm) and after (144.7 +/- 2.8 bpm) cordocenteis was significantly different. The adverse outcome rate was 50.0 per cent (6/12) in cases with bradycardia and 27.7 per cent (26/94) in those without bradycardia (RR=2.6, P=NS). CONCLUSION: Our result is that the association between transient bradycardia following cordocentesis and adverse pregnancy isn't statistically significant, even though adverse outcome is more frequent in pateints with bradycaredia. Therefore, patient with bradycardia following cordocentesis need periodic fetal surveillance. |
| Key Words:
Cordocentesis, Fetal bradycardia, Adverse outcome |
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