A Case of Partial Hydatidiform Mole with Coexisting Twin Pregnancy Following In Vitro Fertilization and Embryo Transfer.

Lee, Yoo Kyung; Sung, Hyo Sook; Hong, Joon Seok; Shim, Soon Sup; Park, Joong Shin; Jun, Jong Kwan; Yoon, Bo Hyun; Syn, Hee Chul

Case Report

Korean Journal of Obstetrics & Gynecology 2004;47(8):1586-1590.
Published online August 1, 2004.

A Case of Partial Hydatidiform Mole with Coexisting Twin Pregnancy Following In Vitro Fertilization and Embryo Transfer.

Yoo Kyung Lee, Hyo Sook Sung, Joon Seok Hong, Soon Sup Shim, Joong Shin Park, Jong Kwan Jun, Bo Hyun Yoon, Hee Chul Syn

Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, Korea.

Abstract

Hydatidiform mole, characterized by abnormal fetoplacental development and placental villous trophoblast hyperplasia, results from genetically abnormal conception. Twin pregnancy consisting of hydatidiform mole (H-mole) and a coexisting fetus occurs with an estimated incidence of 1 per 10,000-100,000 pregnancies. There are several data which H-mole and a coexisting fetus can carry out viable fetus recently. However this unusual pregnancy has the risks of malignant change and severe medical complications, so it is a dilemma to decide continuation or termination of pregnancy. We present a twin pregnancy with partial H-mole and a coexisting fetus that occurred following IVF-ET, which was terminated at 16 weeks of gestation.

Key Words: Twin pregnancy, Hydatidiform mole, Coexisting fetus, IVF-ET