A Case of Primary Malignant Melanoma of Posterior Vaginal Fornix.

Kwak, Kyoung Jin; Jun, Hyun Ah; Kim, Hong Bae; Lee, Keun Young; Kang, Song Won; Yoo, Jong Woo; Park, Hee Chul

Obstet Gynecol Sci > Volume 47(8); 2004 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 2004;47(8):1591-1595.
Published online: August 1, 2004

A Case of Primary Malignant Melanoma of Posterior Vaginal Fornix.

Kyoung Jin Kwak, Hyun Ah Jun, Hong Bae Kim, Keun Young Lee, Song Won Kang, Jong Woo Yoo, Hee Chul Park

¹Department of Obstetrics and Gynecology, College of Medicine, Hallym University, Seoul, Korea.
²Department of Pathology, College of Medicine, Hallym University, Seoul, Korea.
³Department of Radiation Oncology, College of Medicine, Hallym University, Seoul, Korea.

Abstract

Primary malignant melanoma of the vagina is a very rare disease with incidence of 0.026 per 100,000 women. The opinion of several types of treatment is suggested but the prognosis is extremely poor. Although malignant melanoma is generally regarded as a radioresistant tumor, recent reports show that definitive irradiation with high-dose fractionation regimen demonstrates high response rates in primary and metastatic lesions. A case of primary malignant melanoma of the vagina which was treated with intensity-modulated radiation therapy is presented with a brief review of concerned literature.

Keywords: Malignant melanoma; Vagina; Radiation therapy