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Korean Journal of Obstetrics & Gynecology 2004;47(11):2217-2223.
Published online November 1, 2004.
Three cases of Twin-to-Twin Transfusion Syndrome which were managed with maternal digitalization.
Geun A Song, Il Jung Choi, Hyo Jeong Jun, Young A Lee, Moon Seok Cha, Goo Hwa Je
1Department of Obstetrics and Gynecology, Dong-A University, College of Medicine, Busan, Korea.
2Department of Pediatrics, Dong-A University, College of Medicine, Busan, Korea.
Abstract
Twin-to-twin transfusion syndrome (TTTS) is one of the complications showing high mortality rate in monochorionic twins with vascular communication in the placenta. Clinical manifestations of TTTS are usually characterized by polyhydramnios, circulatory overload, cardiac failure and fetal hydrops in the recipient twin and symmetrical fetal growth restriction, oligohydramnios, hypovolemia and anemia in the donor twin. TTTS occurres in 10-35% of monochorionic twins. We report three cases of TTTS with fetal hydrops in which amnioreduction was serially attempted and maternal digoxin treatment was tried for the therapeutic purpose.
Key Words: Twin-to-twin transfusion syndrome (TTTS), Amnioreduction, Digoxin, Fetal therapy


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