A Successful Surrogate Pregnancy in a Patient with Mayer-Rokitansky-Kuster-Hauser Syndrome.

Han, Mi Young; Heo, In Jeong; Park, Hyun Ju; Lee, Hyun Jin; Lee, Eun Hee

Case Report

Korean Journal of Obstetrics & Gynecology 2005;48(6):1533-1539.
Published online June 1, 2005.

A Successful Surrogate Pregnancy in a Patient with Mayer-Rokitansky-Kuster-Hauser Syndrome.

Mi Young Han, In Jeong Heo, Hyun Ju Park, Hyun Jin Lee, Eun Hee Lee

Department of Obstetrics and Gynecology, Ilsin Christian Hospital, Pusan, Korea. gigibe430@hanmail.net

Abstract

Lack of mullerian development (Mayer-Rokitansky-Kuster-Hauser Syndrome) is characterized by absence of apparent vagina and/or uterus, normal secondary sexual characteristics, normal reproductive hormonal profile, and a relatively common cause of primary amenorrhea about 1 in 4,000 female births and also cause of primary infertility. Management for these women comprise of construction of neovagina for sexual life. In 1985, the first report of a successful pregnancy through the uterine surrogacy was made. It is being possible for these women to have new opportunity of getting her own genetic offspring. Since ovarian activity is completely preserved in patients, controlled ovarian hyperstimulation is similar to any other IVF case that is with urinary or recombinant gonadotropins following GnRH agonist down regulation. Genetic offspring can be achieved by cellection of oocytes from the genetic mather, in-vitro-fertilization by the genetic father, and placement into a surrogate carrier. We have experienced a case of successful surrogate pregnancy in a patient with congenital absence of vagina and uterus.

Key Words: Mayer-Rokitansky-Kuster-Hauser Syndrome, Surrogate pregnancy