A case of spontaneous hepatic rupture in a patient with primary hepatocellular carcinoma during the puerperium.

Park, Joon Cheol; Kwon, Sang Hun; Rhee, Jeong Ho; Kim, Jong In

Case Report

Korean Journal of Obstetrics & Gynecology 2005;48(7):1782-1787.
Published online July 1, 2005.

A case of spontaneous hepatic rupture in a patient with primary hepatocellular carcinoma during the puerperium.

Joon Cheol Park, Sang Hun Kwon, Jeong Ho Rhee, Jong In Kim

Department of Obstetrics and Gynecology, School of Medicine, Keimyung University, Daegu, Korea. k1011@dsmc.or.kr

Abstract

Hepatocellular carcinoma associated with pregnancy is rarely encountered, since hepatocellular carcinoma is usually developed after childbearing ages and severe menstrual irregularity and infertility with disturbance of estrogen metabolism is often accompanied with cirrhosis that is a most common underlying disease of primary hepatocellular carcinoma. Spontaneous hepatic rupture in pregnancy is a rare condition associated with significant maternal and perinatal mortality and could be developed related with severe preeclampsia and especially HELLP syndrome but possible related with hepatocellular carcinoma. We report a case of spontaneous hepatic rupture during the puerperium in a patient with hepatocellular carcinoma with a brief review of literatures.

Key Words: Primary hepatocellular carcinoma, Spontaneous hepatic rupture, Puerperium