Fibroadenoma of the Vulva: A Case Report.

Moon, Hyung Bae; Jo, Hyang Jeong; O, Seong Hwan; Hong, Gi Youn

Obstet Gynecol Sci > Volume 48(7); 2005 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 2005;48(7):1816-1819.
Published online July 1, 2005.

Fibroadenoma of the Vulva: A Case Report.

Hyung Bae Moon, Hyang Jeong Jo, Seong Hwan O, Gi Youn Hong

¹Department of Obstetrics and Gynecology, College of Medicine, University of Wonkwang Medical School, Iksan, Korea.
²Department of Pathology and Institute of Wonkwang Medical Science, College of Medicine, University of Wonkwang Medical School, Iksan, Korea. hbmoon@wonkwang.ac.kr
³Department of Pathology, Gunsan Medical Center of Wonkwang University Hospital, Gunsan, Korea.

Abstract

Fibroadenoma is a rare lesion of the vulva. It has been proposed that the origin of the tissue is either ectopic breast tissue or vulvar mammary-like glands (MLG). We report a case of vulvar fibroadenoma in a 33-year-old woman with a right vulvar mass presenting clinically as vulvar cyst. The cut surface of the tumor showed a white and homogenous appearance that was 2.5 cm in maximum dimension. Microscopically, the lesion was well-circumscribed but non-encapsulated. It revealed nodular, glandular and stromal proliferation, consistent with fibroadenoma of breast. Immunohistochemical staining for the estrogen receptor and progesteron receptor revealed nuclear positivity in the epithelium. Smooth muscle actin confirmed the presence of a myoepithelial cell layer. Staining for pancytokeratin showed epithelial cytoplasmic positivity.

Key Words: Vulva, Fibroadenoma, Ectopic breast tissue, Mammary-like glands