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Korean Journal of Obstetrics & Gynecology 2005;48(8):1870-1875.
Published online August 1, 2005.
The usefulness of laparoscopic myomectomy after Hormone Replacement Therapy in postmenopausal women with uterine myoma.
Soo Young Park, Eun Suk Lee, Sung Tack Oh
Department of Obstetrics and Gynecology, College of Medicine, Chonnam National University, Gwangju, Korea. ohst@chonnam.ac.kr
Abstract
OBJECTIVE
This study was undertaken to evaluate the usefulness of laparoscopic myomectomy after hormone replacement therapy in postmenopausal women with uterine myoma. METHODS: The total number of patients with uterine myoma in a postmenopausal women from March 1999 to December 2002 in Department of Obstetrics and Gynecology in Chonnam University Hospital was 137. Patients underwent laparoscopic myomectomy are 12 (Group B) and only hormone replacement therapy without operation are 83 (Group A). The others are not undertaken any treatment (Group C). The number and size of myoma and the development of estrogen-dependent tumor periodically followed up. RESULTS: There were significant differences among three groups with respect to myoma dimension, number. And the risk of developing of estrogen dependent tumor is not increased with Hormone replacement therapy in postmenopausal women. So, laparoscopic myomectomy in a postmenopausal patients would be performed carefully. CONCLUSION: We are not sure whether HRT increases the number and size of the myoma and malignant change when compared with untreated with postmenopausal women. So, laparoscopic myomectomy in a postmenopausal patients would be performed carefully. Further prospective studies with larger groups and a long-term would be helpful in deciding which treatment modality would be appropriate in a postmenopausal patient with myoma.
Key Words: Postmenopause, Hormonal replacement therapy, Laparoscopic myomectomy


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