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Korean Journal of Obstetrics & Gynecology 2006;49(2):357-364.
Published online February 1, 2006.
Normal Reference Range for Cervical Length in Twin Pregnancy using transvaginal ultrasound.
Hye Jin Kim, Joon Seok Hong, Kyo Hoon Park, Ji Ye Jung, Hye Eun Park, Hyun Jun Kim, Sang Hoon Han, Yong Tark Jeon, Byung Chul Jee, Yong Beom Kim, Chang Suk Suh
Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, College of Medicine, Seoul National University, Seoul, Korea. pkh0419@snubh.org
Abstract
OBJECTIVE
We performed prospective longitudinal study to establish reference range for cervical length and evaluate the change in cervix throughout pregnancy in twin pregnancy. METHODS: Fifty-four women of twin pregnancy without history of preterm labor, preterm delivery, cervix cerclage, that delivered at or after 36 weeks were included in this study. Serial measurements of cervical lengths by transvaginal ultrasound exam were performed at 20 weeks of gestation and every 4 weeks (until 28 weeks), every two weeks (until 36 weeks) and every week until delivery. Linear regression analysis was done for statistical analysis. RESULTS: The reference range for cervical length in twin pregnancy was presented as mean, standard deviation and 95% confidence interval of the mean. Cervical length gradually decreased as the gestational age progressed. There was a significant correlation between cervical length measurements and gestational age (Y=71.361-1.336X, r2=0.384, p<0.05). CONCLUSION: We presented the reference range for cervical length in twin pregnancy and evaluated the association between gestational age and cervical length. These results can be used as reference guideline in consecutive assessments of cervical lengths during twin pregnancy.
Key Words: Twin pregnancy, Cervical length, Prospective longitudinal study


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