Two Cases of Granulosa Cell Tumor of the Ovary.

Lee, Hyo Won; Jo, Yoon Young; Cho, Chool Hyun; Kim, Jin; Yu, Seok Dong; Kim, Hyang Mi; Choe, In Duk; Park, Jong Bae; Kang, Haeng Ji

Obstet Gynecol Sci > Volume 49(2); 2006 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 2006;49(2):453-460.
Published online: February 1, 2006

Two Cases of Granulosa Cell Tumor of the Ovary.

Hyo Won Lee, Yoon Young Jo, Chool Hyun Cho, Jin Kim, Seok Dong Yu, Hyang Mi Kim, In Duk Choe, Jong Bae Park, Haeng Ji Kang

¹Department of Obstetrics and Gynecology, Seoul Adventist Hospital, Seoul, Korea. alt3255@hanmail.net
²Department of Pathology, Seoul Adventist Hospital, Seoul, Korea.

Abstract

Granulosa cell tumors are relatively low-grade malignancies accounting for about 1 to 2% of all primary ovarian neoplasms and have an indolent growth pattern. There are two types of tumors, adult type granulosa cell tumor (AGCT) and juvenile type granulosa cell tumor (JGCT), and each tumor reveals different clinical or histopathological features. The clinical manifestations are mostly associated with estrogen produced by tumor, which are vaginal bleeding or menstrual irregularity in AGCT and precocious puberty in JGCT. Although most patients are diagnosed in early stage with favorable prognosis, some recur after several years. So, continuous follow up is required. Recently, we experienced two cases of adult type granulosa cell tumor and report with a brief review of literatures.

Keywords: Adult granulosa cell tumor