A case of ovarian fibrosarcoma with pregnancy.

Lee, Jae Wook; Nam, Eun Ji; Yoon, Bo Sung; Kim, Sang Wun; Kim, Jae Hoon; Kim, Young Tae; Kim, Jae Wook; Kim, Ho Keun; Kim, Sunghoon

Obstet Gynecol Sci > Volume 49(11); 2006 > Article

Case Report

Korean Journal of Obstetrics & Gynecology 2006;49(11):2404-2409.
Published online: November 1, 2006

A case of ovarian fibrosarcoma with pregnancy.

Jae Wook Lee, Eun Ji Nam, Bo Sung Yoon, Sang Wun Kim, Jae Hoon Kim, Young Tae Kim, Jae Wook Kim, Ho Keun Kim, Sunghoon Kim

¹Department of Obstetrics and Gynecology, Women's Cancer Clinic, Yonsei University College of Medicine, Seoul, Korea. shkim70@yumc.yonsei.ac.kr
²Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Ovarian fibromas originating primarily from the ovarian stroma are rare, accounting for approximately 4% of all ovarian neoplasm. The ovarian fibromas are mostly benign tumors, but infrequently they have histologically malignant appearances such as hypercellularity, high mitotic rate, marked nuclear pleomorphism. Malignant fibromatous tumor can be categorized on the basis of prognosis into two separate types of tumors, one of which is cellular fibroma (one to three miotic counts per 10 high power fields) and the other of which is fibrosarcoma (over four miotic counts per 10 high power fields) that has extremely poor prognosis. We report a case of large ovarian fibrosarcoma accompanied with pregnancy and have a brief review of literatures.

Keywords: Ovarian fibrosarcoma; Pregnancy